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Rocky Mountain Environmental Health Association

Research into Multiple Chemical Sensitivity

This page contains the following sections -


This page will present links and reviews of current research into Multiple Chemical Sensitivity.

The Search for Reliable Biomarkers of Disease in Multiple Chemical Sensitivity...

Authors, Chiara De Luca, Desanka Raskovic, et. al.

Originally Published in: Int J Environ Res Public Health, 2011, Jul; 8/7: 2770-2797

The first three authors are with the Tissue Engineering & Skin Pathology Laboratory, Dermatological Research Institute, Via Monti de Creta, Rome 00167, Italy. The Fourth has a comparable position in Malaysia.

This paper begins with a review that, in the midst of a worldwide increase of food and environmental allergies, the world is also facing a inhomogeneous group of environment associated disabling conditions, such as multiple chemistry sensitivity (MCS), fibromyalgia, chronic fatigue syndrome, electric hypersensitivity (EHS), amalgam disease that have no clear-cut allergolic or immunologic involvement. Thus they commonly get ignored by health, political and social systems. Or dismissed aspsychogenic or "medically unexplaind symptoms."

The MCS area has been the target of intensive research that is finding significant alterations of catalase, glutathione-transferase and peroxidase detoxifying activities that correlate with the clinical manifestations of MCS.

A significant limitation in the current research is that there is poor clinical consensus in the classifications in both the wide range of symptoms, and the wide range of environmental aggravants. As a result, the World Health Organization lumped these conditions into the discouaging label of "idiopathic environmental intolerances (IEI)."

This paper suggests that a more appropriate definition would be Sensitivity Related Illnesses (SRI). The SRI illnesses are defined as "adverse clinical states elicited by exposure to low-dose diverse environmental-borne physical triggers."

The following illnesses fall under this classification -

MCS (multiple chemical sensitivity),
FM (Fibromyalgia),
CFS (chronic fatigue syndrome),
IBS (irritable bowel syndrome)
GWS (Persian Gulf War Syndrome),
amalgam disease,
EHS (electromagnetic hypersensivity),
Burn-out syndrome,

The paper then discusses the conceptual difficulties in accepting a disease status that is caused by exposure to aggravants at concentrations far less than the levels used by conventional toxicology. And, we need to be honest with ourselves, and admit that there are the "hinderances, back-shielded by protective interests in the industrial and pharmaceutical world."

Multiple Chemical Sensitivity (MCS)

MCS is commonly described as a multi-organ condition, which includes the following symptoms -

More to come.

References -

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Revised '17-Sep-2017,12:46:30'